Seasonal Variation of Diabetic Ketoacidosis in Nangarhar University Teaching Hospital
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Abstract
Diabetic ketoacidosis is a life threating acute complication of diabetes mellitus aquiring special care. The aim of the study was to find out seasonal variation in the prevalence of diabetic ketoacidosis in diabetic patients. It was a cross sectional hospital based study conducted over both male and female diabetic patients admitter at the internal medicine ward of Nangarhar University Teaching Hospital during one year. Mean age across DKA was 53.9 ± 14 for DKA negative patients versus 51.3 ± 17.2 for DKA positive patients, P value = 0.26. Winter season was demonstrated with peak DKA positive cases 21 (43.7%) followed by fall 6 (22.2%), summer 11 (12.2%) and spring 10 (10.3%), respectively (P value = 0.01). Common associated factors included infection (72.2%), ischemia (8.2%), insulin withdrawal (7.7%), and others (6.9%) though not statistically different across seasons. There was significant seasonal variation in the prevalence of diabetic ketoacidosis denoting winter season with peak diabetic ketoacidosis. In fact, infection followed by ischemia and insulin withdrawal was the leading associated factor contributing to the prevalence of diabetic ketoacidosis. Season specific special attention should be paid the relevant symptoms of diabetic ketoacidosis for the early detection and treatment of the disease in order to avoid morbidity and mortality.
Keywords
Diabetes, Ketoacidosis, Prevalence, Season, Afghanistan##plugins.themes.academic_pro.article.details##
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