Long-term Glucose Infusions had no Influence on Gonadotropins Hormone Secretion in Ovariectomized Goats

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Published Sep 30, 2023
https://doi.org/10.70436/nuijb.v2i03.68
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Vol. 2 No. 03 (2023): September

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Jahid Zabuli
Mohammad Monir Tawfeeq
Tomomi Tanaka
Hideo Kamomae

Abstract

‌Background: It is reported that high nutritional supplementation treatment for seven days stimulated pulsatile LH secretion attended by increased in the plasma glucose and insulin concentrations in goat. The present study tested the hypothesis that whether providing peripheral glucose to goats associated with digestion of high nutrition supplementation increase gonadotropin secretion in ovariectomized goats.
Materials and Methods: There was two experimental groups. The treatment animals from both experiences received glucose infusion. In the first experiment (constant glucose infusion; 50% glucose + saline at a rate of 7.5 ml/h for 7 days) and in the second experiment (progressive glucose infusion; 20% glucose + saline by increasing 5% glucose in 24hr intervals for 7 days at a rate of 15 ml/h for 7 days). The control animals from both experiences received saline infusion in the same manner.
Findings: In the first experiment, there was no significant diversity in the concentrations of glucose and insulin among the treatment period as compared with mean pre-infusion period or compared to control groups except for Day 2 (p<0.05). In the second experiment, concentrations of both the glucose and insulin started increasing significantly from Day 2 and remained with elevated levels until day 7 as compared with mean pre-infusion period or compared to control groups (p<0.05). The mean Follicle stimulating hormone concentration in treatment group was not affected by glucose infusion as compared with pre-infusion periods or control group. The mean LH (concentration and pulse frequency) was not affected by glucose or saline infusion in both experiments.
Conclusion: The present studies suggest that an increase in the glucose availability does not control the gonadotropin secretion as a stimulatory mediator in ovariectomized goats.

Keywords

Glucose infusion, Insulin, Luteinizing hormone, Follicle stimulating hormone, Ovariectomized goats

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How to Cite
Zabuli, J., Tawfeeq, M. M., Tanaka, T., & Kamomae, H. (2023). Long-term Glucose Infusions had no Influence on Gonadotropins Hormone Secretion in Ovariectomized Goats. Nangarhar University International Journal of Biosciences, 2(03), 42–50. https://doi.org/10.70436/nuijb.v2i03.68

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