Chemistry Related to Biology and Medicine

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Published Feb 25, 2023
https://doi.org/10.70436/nuijb.v2i01.27
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Vol. 2 No. 01 (2023): February

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Wali Imam Ulfat
Mati Ur Rehman Yousafzai
Mohammad Agha Dadman
Ziaulhaq Azizi
Khudaidad Kochia

Abstract

Reviewing several facets of Fenton Chemistry's involvement in biology and medicine. There is growing indication that a number of Fenton and Fenton-like reactions can result in the formation of both the OH radical and ferryl . There are a few examples of hydroxyl radical generation that is unrelated to metals. The wood-decaying fungus that causes white rot and brown rot serve as examples of extracellular Fenton reactions. Numerous studies have been published in this area ever since Fenton chemistry and biomedicine were initially linked. Understanding and advancing this topic would be aided by a thorough exposition of the principles of Fenton chemistry and a synopsis of its representative applications in cancer therapy. The current state of Fenton chemistry is then examined, and a few pertinent illustrative instances are provided. Additionally, the current methods for further improving the efficacy of chemotherapy dynamic therapy under the direction of Fenton chemistry are highlighted. The combination of biomedicine and Fenton chemistry or a larger range of catalytic chemistry techniques is given with future possibilities being especially significant. Recently developed reactive oxygen species (ROS) engineered nano catalytic medicines in cancer therapy based on the Fenton reaction, defined as chemical dynamic therapy (CDT), have been extensively studied and made rapid progress. However, the complexity and heterogeneity of tumors reduce the Fenton reaction's ability to oxidize molecules effectively. To increase the effectiveness of CDT and conventional therapeutic approaches, numerous modified tactics, including the Fenton-like reaction and other reactions, are being investigated. This study highlights current developments in the development and use of Fenton nanocatalysts that use the Fenton or modified Fenton reaction for CDT. Also highlighted is the catechol-driven Fenton reaction's natural and useful use.

Keywords

Reactive O2 Species, Redox Cycling, Oxidative Stress, Free Radicals, Carcinogenesis, Fenton Reaction and Chemo Dynamic Therapy

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How to Cite
Ulfat, W. I., Yousafzai, M. U. R., Dadman, M. A., Azizi, Z., & Kochia, K. (2023). Chemistry Related to Biology and Medicine. Nangarhar University International Journal of Biosciences, 2(01), 104–116. https://doi.org/10.70436/nuijb.v2i01.27

References

  1. Barbusiński, K. (2009). Henry John Horstman Fenton-short biography and brief history of Fenton reagent discovery. Chemistry-Didactics-Ecology-Metrology, 14.
  2. Benov, L., & Beema, A. F. (2003). Superoxide-dependence of the short chain sugars-induced mutagenesis. Free Radical Biology and Medicine, 34(4), 429-433.
  3. Bloot, A. P. M., Kalschne, D. L., Amaral, J. A. S., Baraldi, I. J., & Canan, C. (2021). A review of phytic acid sources, obtention, and applications. Food Reviews International, 1-20.
  4. Carter, A., Racey, S., & Veuger, S. (2022). The Role of Iron in DNA and Genomic Instability in Cancer, a Target for Iron Chelators That Can Induce ROS. Applied Sciences, 12(19), 10161.
  5. Chen, J., Yao, J., Li, X. X., Wang, Y., Song, W., Cho, K. B., ... & Wang, B. (2022). Bromoacetic Acid-Promoted Nonheme Manganese-Catalyzed Alkane Hydroxylation Inspired by α-Ketoglutarate-Dependent Oxygenases. ACS Catalysis, 12, 6756-6769.
  6. Cui, J., Shao, S., Gao, J., Yang, Z., Li, L., Zeng, S., ... & Hu, C. (2022). Efficient Single-Atom Fe-Catalyzed Fenton-like Reaction Involving Peroxymonosulfate for BPA Degradation by High-Valent Fe (IV)= O. ACS ES&T Water, 2(12), 2698-2705.
  7. Daniel, I. M., Ishai, O., Daniel, I. M., & Daniel, I. (2006). Engineering mechanics of composite materials (Vol. 1994). New York: Oxford university press.
  8. Deguillaume, L., Leriche, M., & Chaumerliac, N. (2005). Impact of radical versus non-radical pathway in the Fenton chemistry on the iron redox cycle in clouds. Chemosphere, 60(5), 718-724.
  9. Dong, H., Li, Y., Wang, S., Liu, W., Zhou, G., Xie, Y., & Guan, X. (2020). Both Fe (IV) and radicals are active oxidants in the Fe (II)/peroxydisulfate process. Environmental Science & Technology Letters, 7(3), 219-224.
  10. Dixon, S. J., & Stockwell, B. R. (2014). The role of iron and reactive oxygen species in cell death. Nature chemical biology, 10(1), 9-17.)
  11. Dunford, H. B. (2002). Oxidations of iron (II)/(III) by hydrogen peroxide: from aquo to enzyme. Coordination Chemistry Reviews, 233, 311-318.
  12. Engelmann, M. D., Bobier, R. T., Hiatt, T., & Cheng, I. F. (2003). Variability of the Fenton reaction characteristics of the EDTA, DTPA, and citrate complexes of iron. Biometals, 16(4), 519-527.
  13. Fan, J. X., Peng, M. Y., Wang, H., Zheng, H. R., Liu, Z. L., Li, C. X., ... & Zhang, X. Z. (2019). Engineered bacterial bioreactor for tumor therapy via Fenton‐like reaction with localized H2O2 generation. Advanced Materials, 31(16), 1808278.
  14. Gozzo, F. (2001). Radical and non-radical chemistry of the Fenton-like systems in the presence of organic substrates. Journal of molecular catalysis A: Chemical, 171(1-2), 1-22.
  15. Gutteridge, J. M., & Bannister, J. V. (1986). Copper+ zinc and manganese superoxide dismutases inhibit deoxyribose degradation by the superoxide-driven Fenton reaction at two different stages. Implications for the redox states of copper and manganese. Biochemical Journal, 234(1), 225-228.
  16. Halliwell, B., & Gutteridge, J. M. (2015). Free radicals in biology and medicine. Oxford university press, USA.
  17. Hammel, K. E., Kapich, A. N., Jensen Jr, K. A., & Ryan, Z. C. (2002). Reactive oxygen species as agents of wood decay by fungi. Enzyme and microbial technology, 30(4), 445-453.
  18. Haugland, R. A., Schlemm, D. J., Lyons 3rd, R. P., Sferra, P. R., & Chakrabarty, A. M. (1990). Degradation of the chlorinated phenoxyacetate herbicides 2, 4-dichlorophenoxyacetic acid and 2, 4, 5-trichlorophenoxyacetic acid by pure and mixed bacterial cultures. Applied and Environmental Microbiology, 56(5), 1357-1362.
  19. Hollingsworth, Suzanne, "The Effect of Media and Filtration in Inducing the Oxidative Stress Response in Escherichia coli" (2022). University Honors Theses. Paper 1223.
  20. Jay, D., Hitomi, H., & Griendling, K. K. (2006). Oxidative stress and diabetic cardiovascular complications. Free Radical Biology and Medicine, 40(2), 183-192.
  21. Jones, P. (2001). Roles of water in heme peroxidase and catalase mechanisms. Journal of Biological Chemistry, 276(17), 13791-13796.
  22. Jung, Yong Sik, et al. "Effect of pH on Fenton and Fenton‐like oxidation." Environmental Technology 30.2 (2009) 183-190.
  23. Koppenol, W. H. (2022). Ferryl for real. The Fenton reaction near neutral pH. Dalton Transactions, 51(45), 17496-17502.
  24. Liu, M., Liu, B., Liu, Q., Du, K., Wang, Z., & He, N. (2019). Nanomaterial-induced ferroptosis for cancer specific therapy. Coordination Chemistry Reviews, 382, 160-180.
  25. Loegager, T., Holcman, J., Sehested, K., & Pedersen, T. (1992). Oxidation of ferrous ions by ozone in acidic solutions. Inorganic Chemistry, 31(17), 3523-3529.
  26. Metosh-Dickey, C. A., Mason, R. P., & Winston, G. W. (1998). Single electron reduction of xenobiotic compounds by glucose oxidase from Aspergillus niger. Free Radical Biology and Medicine, 24(1), 155-160.
  27. Meng, X., Zhang, X., Liu, M., Cai, B., He, N., & Wang, Z. (2020). Fenton reaction-based nanomedicine in cancer chemodynamic and synergistic therapy. Applied Materials Today, 21, 100864.
  28. Nordberg, J., & Arnér, E. S. (2001). Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. Free radical biology and medicine, 31(11), 1287-1312.
  29. Neelwarne, B., & Rudrappa, T. (2013). Peroxidases and other enzymes from red beet hairy roots. In Red Beet Biotechnology (pp. 283-333). Springer, Boston, MA.
  30. Okado-Matsumoto, A., & Fridovich, I. (2000). The role of α, β-dicarbonyl compounds in the toxicity of short chain sugars. Journal of Biological Chemistry, 275(45), 34853-34857.
  31. Prousek, J. (2007). Fenton chemistry in biology and medicine. Pure and applied chemistry, 79(12), 2325-2338.
  32. Prousek, J. (1995). Fenton reaction after a century. Chemické listy, 89(1), 11-21.
  33. Pryor, W. A. (2006). William A. Pryor, Kendall N. Houk, 2 Christopher S. Foote, 2,† Jon M. Fukuto, 3 Louis J. Ignarro, 3 Giuseppe L. Squadrito, 4 and Kelvin JA Davies5. Am J Physiol Regul Integr Comp Physiol, 291, R491-R511.
  34. Pryshchepa, O., Rafińska, K., Gołębiowski, A., Sugajski, M., Sagandykova, G., Madajski, P., ... & Pomastowski, P. (2022). Synthesis and physicochemical characterization of bovine lactoferrin supersaturated complex with iron (III) ions. Scientific Reports, 12(1), 1-12.
  35. Saran, M., Beck-Speier, I., Fellerhoff, B., & Bauer, G. (1999). Phagocytic killing of microorganisms by radical processes: consequences of the reaction of hydroxyl radicals with chloride yielding chlorine atoms. Free Radical Biology and Medicine, 26(3-4), 482-490.
  36. Tang, Z., Zhao, P., Wang, H., Liu, Y., & Bu, W. (2021). Biomedicine meets Fenton chemistry. Chemical reviews, 121(4), 1981-2019.
  37. Toyokuni, S., Kong, Y., Cheng, Z., Sato, K., Hayashi, S., Ito, F., ... & Akatsuka, S. (2020). Carcinogenesis as side effects of iron and oxygen utilization: from the unveiled truth toward ultimate bioengineering. Cancers, 12(11), 3320.
  38. Valko, M., Rhodes, C. J. B., Moncol, J., Izakovic, M. M., & Mazur, M. (2006). Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chemico-biological interactions, 160(1), 1-40.
  39. Williamson, J., & Davison, G. (2020). Targeted antioxidants in exercise-induced mitochondrial oxidative stress: Emphasis on DNA damage. Antioxidants, 9(11), 1142.
  40. Willson R. L. (1976). Iron, zinc, free radicals and oxygen in tissue disorders and cancer control. Ciba Foundation symposium, (51), 331–354.
  41. Winterbourn, C. C. (1981). Evidence for the production of hydroxyl radicals from the adriamycin semiquinone and H2O2. FEBS Letters, 136(1), 89-94.
  42. Xing, M., Xu, W., Dong, C., Bai, Y., Zeng, J., Zhou, Y., ... & Yin, Y. (2018). Metal sulfides as excellent co-catalysts for H2O2 decomposition in advanced oxidation processes. Chem, 4(6), 1359-1372.
  43. Yeung, A. W. K., Tzvetkov, N. T., El-Tawil, O. S., Bungǎu, S. G., Abdel-Daim, M. M., & Atanasov, A. G. (2019). Antioxidants: scientific literature landscape analysis. Oxidative medicine and cellular longevity, 2019.
  44. Yin, L. L., Yuan, H., Liu, C., He, B., Gao, S. Q., Wen, G. B., ... & Lin, Y. W. (2018). A rationally designed myoglobin exhibits a catalytic dehalogenation efficiency more than 1000-fold that of a native dehaloperoxidase. ACS Catalysis, 8(10), 9619-9624.
  45. Zhao, P., Tang, Z., Chen, X., He, Z., He, X., Zhang, M., ... & Bu, W. (2019). Ferrous-cysteine–phosphotungstate nanoagent with neutral pH fenton reaction activity for enhanced cancer chemodynamic therapy. Materials Horizons, 6(2), 369-374.
  46. Zhu, B. Z., Zhao, H. T., Kalyanaraman, B., & Frei, B. (2002). Metal-independent production of hydroxyl radicals by halogenated quinones and hydrogen peroxide: An ESR spin trapping study. Free Radical Biology and Medicine, 32(5), 465-473.